Principal Officers

Fred N. Eshelman, Pharm.D.

Executive Chairman

David L. Grange

Chief Executive Officer

Daniel G. Darazsdi

Chief Financial Officer, Treasurer and Assistant Secretary

Christine A. Dingivan, M.D.

Executive Vice President and Chief Medical Officer

B. Judd Hartman

General Counsel and Secretary

William W. Richardson

Senior Vice President, Global Business Development

William J. Sharbaugh

Chief Operating Officer

Michael O. Wilkinson

Executive Vice President, Global Clinical Development